diff --git a/acme/acme.go b/acme/acme.go
index 32bebf37a..0c88caae3 100644
--- a/acme/acme.go
+++ b/acme/acme.go
@@ -4,11 +4,13 @@ import (
 	"crypto/tls"
 	"errors"
 	"fmt"
+	"github.com/BurntSushi/ty/fun"
 	"github.com/cenk/backoff"
 	"github.com/containous/staert"
 	"github.com/containous/traefik/cluster"
 	"github.com/containous/traefik/log"
 	"github.com/containous/traefik/safe"
+	"github.com/containous/traefik/types"
 	"github.com/xenolf/lego/acme"
 	"golang.org/x/net/context"
 	"io/ioutil"
@@ -311,22 +313,23 @@ func (a *ACME) CreateLocalConfig(tlsConfig *tls.Config, checkOnDemandDomain func
 }
 
 func (a *ACME) getCertificate(clientHello *tls.ClientHelloInfo) (*tls.Certificate, error) {
+	domain := types.CanonicalDomain(clientHello.ServerName)
 	account := a.store.Get().(*Account)
-	if challengeCert, ok := a.challengeProvider.getCertificate(clientHello.ServerName); ok {
-		log.Debugf("ACME got challenge %s", clientHello.ServerName)
+	if challengeCert, ok := a.challengeProvider.getCertificate(domain); ok {
+		log.Debugf("ACME got challenge %s", domain)
 		return challengeCert, nil
 	}
-	if domainCert, ok := account.DomainsCertificate.getCertificateForDomain(clientHello.ServerName); ok {
-		log.Debugf("ACME got domain cert %s", clientHello.ServerName)
+	if domainCert, ok := account.DomainsCertificate.getCertificateForDomain(domain); ok {
+		log.Debugf("ACME got domain cert %s", domain)
 		return domainCert.tlsCert, nil
 	}
 	if a.OnDemand {
-		if a.checkOnDemandDomain != nil && !a.checkOnDemandDomain(clientHello.ServerName) {
+		if a.checkOnDemandDomain != nil && !a.checkOnDemandDomain(domain) {
 			return nil, nil
 		}
 		return a.loadCertificateOnDemand(clientHello)
 	}
-	log.Debugf("ACME got nothing %s", clientHello.ServerName)
+	log.Debugf("ACME got nothing %s", domain)
 	return nil, nil
 }
 
@@ -429,22 +432,23 @@ func (a *ACME) buildACMEClient(account *Account) (*acme.Client, error) {
 }
 
 func (a *ACME) loadCertificateOnDemand(clientHello *tls.ClientHelloInfo) (*tls.Certificate, error) {
+	domain := types.CanonicalDomain(clientHello.ServerName)
 	account := a.store.Get().(*Account)
-	if certificateResource, ok := account.DomainsCertificate.getCertificateForDomain(clientHello.ServerName); ok {
+	if certificateResource, ok := account.DomainsCertificate.getCertificateForDomain(domain); ok {
 		return certificateResource.tlsCert, nil
 	}
-	certificate, err := a.getDomainsCertificates([]string{clientHello.ServerName})
+	certificate, err := a.getDomainsCertificates([]string{domain})
 	if err != nil {
 		return nil, err
 	}
-	log.Debugf("Got certificate on demand for domain %s", clientHello.ServerName)
+	log.Debugf("Got certificate on demand for domain %s", domain)
 
 	transaction, object, err := a.store.Begin()
 	if err != nil {
 		return nil, err
 	}
 	account = object.(*Account)
-	cert, err := account.DomainsCertificate.addCertificateForDomains(certificate, Domain{Main: clientHello.ServerName})
+	cert, err := account.DomainsCertificate.addCertificateForDomains(certificate, Domain{Main: domain})
 	if err != nil {
 		return nil, err
 	}
@@ -456,6 +460,7 @@ func (a *ACME) loadCertificateOnDemand(clientHello *tls.ClientHelloInfo) (*tls.C
 
 // LoadCertificateForDomains loads certificates from ACME for given domains
 func (a *ACME) LoadCertificateForDomains(domains []string) {
+	domains = fun.Map(types.CanonicalDomain, domains).([]string)
 	safe.Go(func() {
 		operation := func() error {
 			if a.client == nil {
@@ -514,6 +519,7 @@ func (a *ACME) LoadCertificateForDomains(domains []string) {
 }
 
 func (a *ACME) getDomainsCertificates(domains []string) (*Certificate, error) {
+	domains = fun.Map(types.CanonicalDomain, domains).([]string)
 	log.Debugf("Loading ACME certificates %s...", domains)
 	bundle := true
 	certificate, failures := a.client.ObtainCertificate(domains, bundle, nil)
diff --git a/rules.go b/rules.go
index c091e0fa6..96cc73b6e 100644
--- a/rules.go
+++ b/rules.go
@@ -3,7 +3,9 @@ package main
 import (
 	"errors"
 	"fmt"
+	"github.com/BurntSushi/ty/fun"
 	"github.com/containous/mux"
+	"github.com/containous/traefik/types"
 	"net"
 	"net/http"
 	"reflect"
@@ -24,7 +26,7 @@ func (r *Rules) host(hosts ...string) *mux.Route {
 			reqHost = req.Host
 		}
 		for _, host := range hosts {
-			if reqHost == strings.TrimSpace(host) {
+			if types.CanonicalDomain(reqHost) == types.CanonicalDomain(host) {
 				return true
 			}
 		}
@@ -35,7 +37,7 @@ func (r *Rules) host(hosts ...string) *mux.Route {
 func (r *Rules) hostRegexp(hosts ...string) *mux.Route {
 	router := r.route.route.Subrouter()
 	for _, host := range hosts {
-		router.Host(strings.TrimSpace(host))
+		router.Host(types.CanonicalDomain(host))
 	}
 	return r.route.route
 }
@@ -43,7 +45,7 @@ func (r *Rules) hostRegexp(hosts ...string) *mux.Route {
 func (r *Rules) path(paths ...string) *mux.Route {
 	router := r.route.route.Subrouter()
 	for _, path := range paths {
-		router.Path(strings.TrimSpace(path))
+		router.Path(types.CanonicalDomain(path))
 	}
 	return r.route.route
 }
@@ -51,7 +53,7 @@ func (r *Rules) path(paths ...string) *mux.Route {
 func (r *Rules) pathPrefix(paths ...string) *mux.Route {
 	router := r.route.route.Subrouter()
 	for _, path := range paths {
-		router.PathPrefix(strings.TrimSpace(path))
+		router.PathPrefix(types.CanonicalDomain(path))
 	}
 	return r.route.route
 }
@@ -67,7 +69,7 @@ func (r *Rules) pathStrip(paths ...string) *mux.Route {
 	r.route.stripPrefixes = paths
 	router := r.route.route.Subrouter()
 	for _, path := range paths {
-		router.Path(strings.TrimSpace(path))
+		router.Path(types.CanonicalDomain(path))
 	}
 	return r.route.route
 }
@@ -77,7 +79,7 @@ func (r *Rules) pathPrefixStrip(paths ...string) *mux.Route {
 	r.route.stripPrefixes = paths
 	router := r.route.route.Subrouter()
 	for _, path := range paths {
-		router.PathPrefix(strings.TrimSpace(path))
+		router.PathPrefix(types.CanonicalDomain(path))
 	}
 	return r.route.route
 }
@@ -153,7 +155,6 @@ func (r *Rules) parseRules(expression string, onRule func(functionName string, f
 		}
 	}
 	return nil
-
 }
 
 // Parse parses rules expressions
@@ -197,5 +198,5 @@ func (r *Rules) ParseDomains(expression string) ([]string, error) {
 	if err != nil {
 		return nil, fmt.Errorf("Error parsing domains: %v", err)
 	}
-	return domains, nil
+	return fun.Map(types.CanonicalDomain, domains).([]string), nil
 }
diff --git a/rules_test.go b/rules_test.go
index 2bb89a347..694fde089 100644
--- a/rules_test.go
+++ b/rules_test.go
@@ -36,7 +36,7 @@ func TestParseTwoRules(t *testing.T) {
 	serverRoute := &serverRoute{route: route}
 	rules := &Rules{route: serverRoute}
 
-	expression := "Host:foo.bar;Path:/foobar"
+	expression := "Host: Foo.Bar ; Path:/FOObar"
 	routeResult, err := rules.Parse(expression)
 
 	if err != nil {
@@ -58,11 +58,13 @@ func TestParseDomains(t *testing.T) {
 		"Host:foo.bar,test.bar",
 		"Path:/test",
 		"Host:foo.bar;Path:/test",
+		"Host: Foo.Bar ;Path:/test",
 	}
 	domainsSlice := [][]string{
 		{"foo.bar", "test.bar"},
 		{},
 		{"foo.bar"},
+		{"foo.bar"},
 	}
 	for i, expression := range expressionsSlice {
 		domains, err := rules.ParseDomains(expression)
diff --git a/types/types.go b/types/types.go
index b9d8298f8..76fa96bd4 100644
--- a/types/types.go
+++ b/types/types.go
@@ -223,3 +223,8 @@ type Basic struct {
 type Digest struct {
 	Users
 }
+
+// CanonicalDomain returns a lower case domain with trim space
+func CanonicalDomain(domain string) string {
+	return strings.ToLower(strings.TrimSpace(domain))
+}